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Reserve concomitant prescribing of these medicine in sufferers for whom other therapy options are inadequate. Limit dosages and durations to the minimum necessary. Observe closely for indications of respiratory despair and sedation. isoniazid will boost the amount or result of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Monitor http://tramadol 225mg

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