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Renal clearance of cotinine is significantly less compared to the glomerular filtration fee (Benowitz et al. 2008b). Considering that cotinine is not really appreciably protein sure, this means considerable tubular reabsorption. Renal clearance of cotinine can be Increased by nearly fifty% with Extraordinary urinary acidification. Cotinine excretion is less affected https://mrdistro.com/

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